BNV Biolab have created MPF™ technology (human cell-derived signaling molecules) and launched world’s first 4 types of rejuvenating solutions with 12 finest doctors to prove its regenerative capability. We promise to supply safe and effective products at reasonable cost and continue to find most efficient way to resolve aging problems.
MPF™ are signaling protein factors developed using proteomic technology to enhance skin tissue regeneration by replenishing required protein factors for wound healing process. Unlike basic nutrients, MPF™ can carry out cell to cell communication and used to treat aging and damaged skin.
Wound healing effects of MPF™
Result from the wound healing assay shows that MPF™ treated fibroblast grows twice as fast as fibroblasts treated with basic nutrients and complete wound closure was observed in MPF™ treated fibroblasts.
MPF™ contains multiple protein factors necessary for cell regeneration. This study proved efficacy of the solution during the wound healing process and also confirmed that effect of MPF™ was superior compared to the cell media EGF, FGF with basic nutrients.
Proteomic analysis (2D gel electrophoresis)
2D gel Experiment showed that MPF™ includes more than 200 proteins whereas basic nutrients has no protein.
4 step wound healing process and necessary signaling molecules
Emergent repair system activated to stop bleeding by forming blood clots.
defensive system is activated to prevent infection and prepare for the growth of new tissue.
connective tissue and new blood vessels are formed and epithelialization occurs.
new tissue gains strength and flexibility. Collagen fibers reorganize and increases tensile strength.
Figure 1. Exosome contents of MPF™ positive for CD63 exosome marker.
The result of exosome detection in MPF™ showed that approximately 1.7×109 exosome particles per 1ml of MPF™ were contained (Figure 1).
Flgure 2. Fibroblast Cell
From this exosome detection study, it was confirmed that the exosomes used during cellular metabolism are contained in BNV Biolab’s MPF™