TECHNOLOGY

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MPF™

Multi-Peptide-Fator

BNV Biolab have created MPF™ technology (human cell-derived signaling molecules) and launched world’s first 4 types of rejuvenating solutions with 12 finest doctors to prove its regenerative capability. We promise to supply safe and effective products at reasonable cost and continue to find most efficient way to resolve aging problems.

MPF1

MPF™ are signaling protein factors developed using proteomic technology to enhance skin tissue regeneration by replenishing required protein factors for wound healing process. Unlike basic nutrients, MPF™ can carry out cell to cell communication and used to treat aging and damaged skin.

Wound healing effects of MPF™

Results

Result from the wound healing assay shows that MPF™ treated fibroblast grows twice as fast as fibroblasts treated with basic nutrients and complete wound closure was observed in MPF™ treated fibroblasts.

Conclusions

MPF™ contains multiple protein factors necessary for cell regeneration. This study proved efficacy of the solution during the wound healing process and also confirmed that effect of MPF™ was superior compared to the cell media EGF, FGF with basic nutrients.

MPF2

Proteomic analysis (2D gel electrophoresis)

Results

2D gel Experiment showed that MPF™ includes more than 200 proteins whereas basic nutrients has no protein.

MPF3

4 step wound healing process and necessary signaling molecules

1.Hemostasis

Emergent repair system activated to stop bleeding by forming blood clots.

2.Inflammation

defensive system is activated to prevent infection and prepare for the growth of new tissue.

3.Proliferation

connective tissue and new blood vessels are formed and epithelialization occurs.

5. Maturity

new tissue gains strength and flexibility. Collagen fibers reorganize and increases tensile strength.

WOUND HEALING 5
MPF4

Figure 1. Exosome contents of MPF™ positive for CD63 exosome marker.

Results

The result of exosome detection in MPF™ showed that approximately 1.7×109 exosome particles per 1ml of MPF™ were contained (Figure 1).

MPF5

Flgure 2. Fibroblast Cell

Conclusions

From this exosome detection study, it was confirmed that the exosomes used during cellular metabolism are contained in BNV Biolab’s MPF™